(-)-Pinoresinol 4-O-glucoside( —— )

Catalog No. M31550 CAS No. 41607-20-9

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Product Name

(-)-Pinoresinol 4-O-glucoside
Note

Research use only, not for human use.
Brief Description

(-)-Pinoresinol 4-O-glucoside is a natural product from Lonicera japonica THUNB.
Description

(-)-Pinoresinol 4-O-glucoside is a natural product from Lonicera japonica THUNB.
In Vitro

RT-PCR Cell Line:pre-osteoblasts Concentration:10, 30 μM Incubation Time:3 days Result:Upregulated the mRNA level of BMP2 and its target osteoblast genes, ALP and osteocalcin (OCN).Western Blot Analysis Cell Line:pre-osteoblasts Concentration:10, 30 μM Incubation Time:3 days Result:Enhanced protein level of BMP2, followed by the phosphorylation of Smad1/5/8 and the expression of RUNX2.
In Vivo

Animal Model:27-30 g, Male Swiss albino miceDosage:50 mg/kg Administration:P.o.; twenty days Result:Exhibited a hepatoprotective activity in vivo as it lowered AST and ALT levels, caused a prominent decline in serum glucose level by 37.83% in streptozotocin-treated mice with promising elevation in insulin level of 25.37%.
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